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. 2019 Jul 26;10:850. doi: 10.3389/fphar.2019.00850

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Copyright © 2019 Chen, Gao, Jiao, Qiu, Wang, Yu, Che, Li, Liu, Li, Zhang, Yu, Li, Gao, Pan, Sun, Guo, Cao, Zhu and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Atherosclerotic (AS) formation of ApoE^−/− mice after a high-fat diet for 13 weeks compared with C57BL/6 mice by “En face” observation. (B) AS formation of ApoE^−/− mice after a high-fat diet for 13 weeks compared with C57BL/6 mice by hematoxylin–eosin (H&E) staining on light microscope. CON: C57BL/6 mice, MOD: ApoE^−/− mice (bar = 500 µm).