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H99-α infected mice showed higher cDC1 and monocyte activation compared with H99 infected mice. Isolated lung leukocytes from infected mice were analyzed by flow cytometry. The surface expression levels of CD80 or MHCII were measured. (A,B) H99-α induced a higher frequency of cDC1 population producing CD80 on 14 and 21 dpi. (C,D) H99-α induced elevated frequency of monocytes producing MHCII at 21 dpi. Results represent mean ± SEM; N = 4 or more mice per group (*P < 0.05).
