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. 2019 Aug;67(8):1265–1277. doi: 10.4103/ijo.IJO_117_19

Table 2.

Summary of published studies on outcomes of simple limbal epithelial transplantation (SLET) for the treatment of various ocular surface pathologies

Most common indication (number of eyes) Author Year Country Study design Total number of eyes Amount of limbal tissue harvested Success rate in percentage (Number of eyes) Percentage of eyes with 2-line improvement in BCVA (Number of eyes) Percentage of eyes which underwent simultaneous/ subsequent LK/PK Mean follow-up in years (range)
Chemical burn (5) Sangwan et al.[10] 2012 India R 6 2×2 mm/1 clock h 100 (6/6) 100 (6/6) None 0.8 (0.6-1)
Chemical burn (2) Amescua et al.[14] 2014 U.S.A R 4 2×2 mm/1 clock h 100 (4/4) NA None 0.6 (0.5-0.75)
Simultaneously after primary pterygium excision (9) Hernadez- Bogantes et al.[17] 2015 Mexico R 9 2×2 mm from ipsilateral eye 100 (9/9) NA NA 0.67
Chemical burn (125) Basu et al.[11] 2016 India P 125 2×2 mm/1 clock h 76 (95/125) 75 (94/125) 8 (10/125) 1.5 (1-4)
Chemical burn (62) Vazirani et al.[12] 2016 Multi-centre R 68 1-2 clock hours 84 (57/68) 65 (44/68) 7 (5/68) 1 (0.5-4.9)
Chemical burn (4) Quieroz et al.[29] 2016 Brazil R 4 4×2 mm 50 (2/4) 24 (1/4) None 0.5
Chemical burn (26) Gupta et al.[13] 2018 India P 30 1-2 clock h 70 (21/30) 50 (15/30) 10 (3/30) 1.1 (0.5-3.4)
Simultaneously after OSSN excision (8) Kaliki et al.[15] 2017 India R 8 1 clock hour from ipsilateral or contralateral eye 100 (8/8) NA NA 1
Simultaneously after recurrent pterygium excision (4) Mednick et al.[18] 2018 Canada R 4 4×2mm 100 (4/4) NA NA 1.2 (0.7-2.5)
Chemical burn-eyes with previous failed CLET (30) Basu et al.[20] 2018 India R 30 1 clock h 80 (24/30) NA 13 (4/30) 2.3 (0.8-3.8)

OSSN=ocular surface squamous neoplasia; R=retrospective; P=prospective; SLET=simple limbal epithelial transplantation; BCVA=best-corrected visual acuity; LK=lamellar keratoplasty; PK=penetrating keratoplasty; NA=not applicable; CLET=Cultivated limbal epithelial transplantation