Table 2.
Most common indication (number of eyes) | Author | Year | Country | Study design | Total number of eyes | Amount of limbal tissue harvested | Success rate in percentage (Number of eyes) | Percentage of eyes with 2-line improvement in BCVA (Number of eyes) | Percentage of eyes which underwent simultaneous/ subsequent LK/PK | Mean follow-up in years (range) |
---|---|---|---|---|---|---|---|---|---|---|
Chemical burn (5) | Sangwan et al.[10] | 2012 | India | R | 6 | 2×2 mm/1 clock h | 100 (6/6) | 100 (6/6) | None | 0.8 (0.6-1) |
Chemical burn (2) | Amescua et al.[14] | 2014 | U.S.A | R | 4 | 2×2 mm/1 clock h | 100 (4/4) | NA | None | 0.6 (0.5-0.75) |
Simultaneously after primary pterygium excision (9) | Hernadez- Bogantes et al.[17] | 2015 | Mexico | R | 9 | 2×2 mm from ipsilateral eye | 100 (9/9) | NA | NA | 0.67 |
Chemical burn (125) | Basu et al.[11] | 2016 | India | P | 125 | 2×2 mm/1 clock h | 76 (95/125) | 75 (94/125) | 8 (10/125) | 1.5 (1-4) |
Chemical burn (62) | Vazirani et al.[12] | 2016 | Multi-centre | R | 68 | 1-2 clock hours | 84 (57/68) | 65 (44/68) | 7 (5/68) | 1 (0.5-4.9) |
Chemical burn (4) | Quieroz et al.[29] | 2016 | Brazil | R | 4 | 4×2 mm | 50 (2/4) | 24 (1/4) | None | 0.5 |
Chemical burn (26) | Gupta et al.[13] | 2018 | India | P | 30 | 1-2 clock h | 70 (21/30) | 50 (15/30) | 10 (3/30) | 1.1 (0.5-3.4) |
Simultaneously after OSSN excision (8) | Kaliki et al.[15] | 2017 | India | R | 8 | 1 clock hour from ipsilateral or contralateral eye | 100 (8/8) | NA | NA | 1 |
Simultaneously after recurrent pterygium excision (4) | Mednick et al.[18] | 2018 | Canada | R | 4 | 4×2mm | 100 (4/4) | NA | NA | 1.2 (0.7-2.5) |
Chemical burn-eyes with previous failed CLET (30) | Basu et al.[20] | 2018 | India | R | 30 | 1 clock h | 80 (24/30) | NA | 13 (4/30) | 2.3 (0.8-3.8) |
OSSN=ocular surface squamous neoplasia; R=retrospective; P=prospective; SLET=simple limbal epithelial transplantation; BCVA=best-corrected visual acuity; LK=lamellar keratoplasty; PK=penetrating keratoplasty; NA=not applicable; CLET=Cultivated limbal epithelial transplantation