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. 2019 Mar 18;3(4):521–531. doi: 10.1002/bjs5.50154

Table 2.

Univariable analysis of overall and disease‐free survival

Overall survival Disease‐free survival
n Median(months) P n Median (months) P
Age (years) < 55 76 101 0·155 75 18 0·941
≥ 55 and < 65 103 80 101 18
≥ 65 and < 75 108 53 108 14
≥ 75 66 40 66 13
Sex F 129 106 0·059 126 22 0·049
M 224 58 224 15
Site of primary tumour Colon 237 65 0·483 234 16 0·618
Rectum 115 74 115 16
Temporal relationship Synchronous 180 48 0·073 177 11 0·004
Metachronous 173 95 173 23
Dukes' class A/B 112 68 0·291 111 23 0·205
C 216 60 215 15
Primary surgery complication No 297 68 0·082 296 18 0·088
Yes 234 48 34 11
Preoperative chemotherapy No 97 68 0·624 96 23 0·111
Yes 255 65 253 13
Resection type Anatomical 189 48 0·004 187 15 0·045
Non‐anatomical 164 141 163 18
Pringle manoeuvre No 47 106 0·932 46 21 0·336
Yes 272 65 270 16
Tumour size (cm) < 2·5 131 74 0·008 131 18 0·145
≥ 2·5 and < 5·0 123 80 122 17
≥ 5·0 and < 10·0 83 39 81 10
≥ 10·0 16 36 16 14
No. of tumours Solitary 170 82 0·019 170 24 < 0·001
Multiple 183 49 180 11
Duration of surgery (h)* ≤ 2 93 (37) 0·013 93 19 0·157
> 2 and ≤ 3 99 101 (30) 98 15
> 3 and ≤ 4 79 53 (26) 77 13
> 4 50 46 (18) 50 13
Estimated blood loss (ml) < 100 89 101 0·078 89 18 0·126
≥ 100 and < 200 88 106 87 23
≥ 200 and < 400 81 60 80 15
≥ 400 81 46 80 10
Blood transfusion No 328 72 0·004 325 16 0·285
Yes 21 31 21 16
Hospital stay (days) ≤ 7 176 92 0·014 173 21 0·030
> 7 and ≤ 14 146 52 146 13
> 14 28 46 28 9
Complications None or minor 296 79 0·007 293 18 0·056
Major 57 38 57 11
Resection margin R0 295 80 0·011 293 18 0·027
R1 58 43 57 11
*

Values in parentheses represent the 25 per cent quantile as the median was not reached during the study period for all groups.

Log rank test.