Table 2.
Overall survival | Disease‐free survival | ||||||
---|---|---|---|---|---|---|---|
n | Median(months) | P † | n | Median (months) | P † | ||
Age (years) | < 55 | 76 | 101 | 0·155 | 75 | 18 | 0·941 |
≥ 55 and < 65 | 103 | 80 | 101 | 18 | |||
≥ 65 and < 75 | 108 | 53 | 108 | 14 | |||
≥ 75 | 66 | 40 | 66 | 13 | |||
Sex | F | 129 | 106 | 0·059 | 126 | 22 | 0·049 |
M | 224 | 58 | 224 | 15 | |||
Site of primary tumour | Colon | 237 | 65 | 0·483 | 234 | 16 | 0·618 |
Rectum | 115 | 74 | 115 | 16 | |||
Temporal relationship | Synchronous | 180 | 48 | 0·073 | 177 | 11 | 0·004 |
Metachronous | 173 | 95 | 173 | 23 | |||
Dukes' class | A/B | 112 | 68 | 0·291 | 111 | 23 | 0·205 |
C | 216 | 60 | 215 | 15 | |||
Primary surgery complication | No | 297 | 68 | 0·082 | 296 | 18 | 0·088 |
Yes | 234 | 48 | 34 | 11 | |||
Preoperative chemotherapy | No | 97 | 68 | 0·624 | 96 | 23 | 0·111 |
Yes | 255 | 65 | 253 | 13 | |||
Resection type | Anatomical | 189 | 48 | 0·004 | 187 | 15 | 0·045 |
Non‐anatomical | 164 | 141 | 163 | 18 | |||
Pringle manoeuvre | No | 47 | 106 | 0·932 | 46 | 21 | 0·336 |
Yes | 272 | 65 | 270 | 16 | |||
Tumour size (cm) | < 2·5 | 131 | 74 | 0·008 | 131 | 18 | 0·145 |
≥ 2·5 and < 5·0 | 123 | 80 | 122 | 17 | |||
≥ 5·0 and < 10·0 | 83 | 39 | 81 | 10 | |||
≥ 10·0 | 16 | 36 | 16 | 14 | |||
No. of tumours | Solitary | 170 | 82 | 0·019 | 170 | 24 | < 0·001 |
Multiple | 183 | 49 | 180 | 11 | |||
Duration of surgery (h)* | ≤ 2 | 93 | (37) | 0·013 | 93 | 19 | 0·157 |
> 2 and ≤ 3 | 99 | 101 (30) | 98 | 15 | |||
> 3 and ≤ 4 | 79 | 53 (26) | 77 | 13 | |||
> 4 | 50 | 46 (18) | 50 | 13 | |||
Estimated blood loss (ml) | < 100 | 89 | 101 | 0·078 | 89 | 18 | 0·126 |
≥ 100 and < 200 | 88 | 106 | 87 | 23 | |||
≥ 200 and < 400 | 81 | 60 | 80 | 15 | |||
≥ 400 | 81 | 46 | 80 | 10 | |||
Blood transfusion | No | 328 | 72 | 0·004 | 325 | 16 | 0·285 |
Yes | 21 | 31 | 21 | 16 | |||
Hospital stay (days) | ≤ 7 | 176 | 92 | 0·014 | 173 | 21 | 0·030 |
> 7 and ≤ 14 | 146 | 52 | 146 | 13 | |||
> 14 | 28 | 46 | 28 | 9 | |||
Complications | None or minor | 296 | 79 | 0·007 | 293 | 18 | 0·056 |
Major | 57 | 38 | 57 | 11 | |||
Resection margin | R0 | 295 | 80 | 0·011 | 293 | 18 | 0·027 |
R1 | 58 | 43 | 57 | 11 |
Values in parentheses represent the 25 per cent quantile as the median was not reached during the study period for all groups.
Log rank test.