Table 3.
Final doubly robust multivariable model for overall and disease‐free survival
| Hazard ratio | s.e. | P | |
|---|---|---|---|
| Overall survival | |||
| Resection type | 0·537 | ||
| Non‐anatomical | 1·00 (reference) | ||
| Anatomical | 1·21 (0·62, 1·28) | 0·17 | |
| Tumour size (cm) | 0·035 | ||
| < 2·5 | 1·00 (reference) | ||
| ≥ 2·5 and < 5·0 | 1·09 (0·75, 1·59) | 0·21 | |
| ≥ 5·0 and < 10·0 | 1·81 (1·13, 2·90) | 0·44 | |
| ≥ 10 | 2·17 (1·08, 4·34) | 0·77 | |
| No. of tumours | 0·035 | ||
| Solitary | 1·00 (reference) | ||
| Multiple | 1·48 (1·03, 2·12) | 0·27 | |
| Resection margin | 0·102 | ||
| R0 | 1·00 (reference) | ||
| R1 | 1·42 (0·93, 2·16) | 0·30 | |
| Disease‐free survival | |||
| Resection type | 0·429 | ||
| Non‐anatomical | 1·00 (reference) | ||
| Anatomical | 1·12 (0·67, 1·18) | 0·13 | |
| Temporal relationship | 0·045 | ||
| Metachronous | 1·00 (reference) | ||
| Synchronous | 1·33 (1·01, 1·77) | 0·19 | |
| Primary surgery complication | 0·045 | ||
| No | 1·00 (reference) | ||
| Yes | 1·51 (1·01, 2·26) | 0·31 | |
| Complications at liver resection | 0·026 | ||
| None or minor | 1·00 (reference) | ||
| Major | 1·49 (1·05, 2·11) | 0·26 | |
| No. of tumours | 0·004 | ||
| Solitary | 1·00 (reference) | ||
| Multiple | 1·51 (1·14, 2·00) | 0·22 | |
| Resection margin | 0·092 | ||
| R0 | 1·00 (reference) | ||
| R1 | 1·34 (0·95, 1·90) | 0·24 |
Values in parentheses are 95 per cent confidence intervals.