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. 2019 Jul 24;10:1735. doi: 10.3389/fimmu.2019.01735

Table 2.

The frequencies of BCP and preC mutations between rt269L and rt269I in a Korean cohort and from reference strains.

Mutation Nucleotide Clinical isolates Reference strains
rt269L (n = 115) rt269I (n = 69) p-value rt269L (n = 111) rt269I (n = 129) p-value
BCP mutation A1762T A 47 (40.87%) 23 (33.33%) ns 31(27.93%) 24 (18.60%) ns
T 68 (59.13%) 46 (66.67%) 80(72.07%) 105 (81.40%)
G1764A G 44 (38.26%) 16 (23.19%) * 29(26.13%) 17 (13.18%) *
A 71 (61.73%) 53 (76.81%) 82(73.87%) 112 (86.82%)
preC mutation G1896A G 83 (72.17%) 33 (47.83%) *** 79(71.17%) 65 (50.39%) ***
A 32 (27.83%) 36 (52.17%) 32(28.83%) 64 (49.61%)

BCP, basal core promoter; preC, pre-core.

Continuous variables were tested using the chi-squared test. ns, non-significant;

*

p < 0.05; **p < 0.01;

***

p < 0.001.