Table 2.
The frequencies of BCP and preC mutations between rt269L and rt269I in a Korean cohort and from reference strains.
Mutation | Nucleotide | Clinical isolates | Reference strains | |||||
---|---|---|---|---|---|---|---|---|
rt269L (n = 115) | rt269I (n = 69) | p-value | rt269L (n = 111) | rt269I (n = 129) | p-value | |||
BCP mutation | A1762T | A | 47 (40.87%) | 23 (33.33%) | ns | 31(27.93%) | 24 (18.60%) | ns |
T | 68 (59.13%) | 46 (66.67%) | 80(72.07%) | 105 (81.40%) | ||||
G1764A | G | 44 (38.26%) | 16 (23.19%) | * | 29(26.13%) | 17 (13.18%) | * | |
A | 71 (61.73%) | 53 (76.81%) | 82(73.87%) | 112 (86.82%) | ||||
preC mutation | G1896A | G | 83 (72.17%) | 33 (47.83%) | *** | 79(71.17%) | 65 (50.39%) | *** |
A | 32 (27.83%) | 36 (52.17%) | 32(28.83%) | 64 (49.61%) |
BCP, basal core promoter; preC, pre-core.
Continuous variables were tested using the chi-squared test. ns, non-significant;
p < 0.05; **p < 0.01;
p < 0.001.