TABLE 1. Preintervention prevalence of human immunodeficiency virus (HIV) infection among residents aged 18–49 years; preintervention prevalence of prior diagnosis of HIV infection, current enrollment in HIV care, and current use of antiretroviral therapy (ART) among HIV-positive residents aged 18–49 years; and intervention targets and outcomes — Bukoba Combination Prevention Evaluation, Bukoba Municipal Council, Tanzania, 2014–2017*.
Characteristic | Preintervention prevalence estimates (Nov 2013–Jan 2014)† |
Intervention targets and outcomes (Oct 2014–May 2017)§ |
|||||||
---|---|---|---|---|---|---|---|---|---|
HIV-positive |
Prior HIV diagnosis |
Currently in HIV care |
Currently using ART |
HIV-positive (total residents) |
Need HIV diagnosis |
HIV infection diagnosed¶ |
Need HIV care |
Enrolled in HIV care¶ |
|
% (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | No. (no.) | No. (%)** | No. (%)†† | No. (%)** | No. (%)§§ | |
Total
|
8.9 (7.5–10.4)
|
47.4 (41.3–53.4)
|
40.8 (34.9–46.8)
|
32.2 (26.4–38.0)
|
5,903 (66,134)
|
3,107 (53)
|
3,381 (109)
|
3,493 (59)
|
3,488 (100)
|
Sex
| |||||||||
Men |
6.8 (5.2–8.4) |
36.8 (28.0–45.5) |
28.3 (20.0–36.6) |
23.0 (14.9–31.1) |
2,193 (32,435) |
1,387 (63) |
1,269 (91) |
1,573 (72) |
1,346 (86) |
Women |
11.0 (9.2–12.8) |
53.6 (47.5–59.8) |
48.3 (42.2–54.3) |
37.7 (31.2–44.1) |
3,710 (33,699) |
1,720 (46) |
2,112 (123) |
1,920 (52) |
2,142 (112) |
Age group (yrs)
| |||||||||
18–24 |
3.9 (3.0–4.7) |
28.8 (18.0–39.5) |
23.2 (12.9–33.6) |
15.4 (7.2–23.5) |
856 (22,199) |
609 (71) |
809 (133) |
657 (77) |
737 (112) |
25–49 | 11.5 (9.6–13.4) | 50.5 (44.1–56.9) | 43.8 (37.8–49.9) | 35.1 (29.0–41.2) | 5,047 (43,935) | 2,498 (49) | 2572 (103) | 2,836 (56) | 2,751 (97) |
Abbreviation: CI = confidence interval.
* A community-wide combination prevention intervention was implemented throughout Bukoba Municipal Council during October 2014–March 2017 (Supplementary Figure, https://stacks.cdc.gov/view/cdc/80050). New interventions included comprehensive medical outpatient department and home- and venue-based HIV testing services; peer-delivered linkage case management for all consenting HIV-positive persons referred to 11 participating health care facilities; and defaulter-tracing services for patients at participating facilities who had not received HIV care in the prior 90 days during October 2014–March 2017. Recruitment into linkage case management ended March 30, 2017, and management services ended May 31, 2017.
† The preintervention survey was conducted in census enumeration areas of Bukoba Municipal Council randomly selected in proportion to ward population in each of the 14 administrative wards. All household members aged 18–49 years were eligible to participate in a personal interview and test for HIV infection by the national rapid HIV test algorithm. Prevalence outcomes were estimated with SURVEYFREQ procedures, weighted by sex, age group, and geographic area of the Bukoba Municipal Council census and adjusted for clustering within census enumeration areas using SAS (version 9.3; SAS Institute). Prior diagnosis of HIV infection, and current enrollment in HIV care and use of ART (conditions) included persons with HIV infection who either 1) reported these conditions as part of the standard survey interview; 2) were confirmed by medical record to have these conditions; or 3) had achieved viral load suppression (<1,000 HIV RNA copies/μL). Conditions included viral load suppression because of low sensitivity (77%) of self-reported ART use (https://www.ncbi.nlm.nih.gov/pubmed/29194115) and that only 1% of persons with HIV achieve durable viral load suppression in the absence of ART adherence (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904947/). Percentages of conditions are of persons with HIV infection.
§ Bukoba Municipal Council census estimates were obtained from the Tanzania National Bureau of Statistics (https://www.nbs.go.tz/index.php/en/). Total residents = estimated census of residents aged 18–49 years. No. of HIV-positive residents = total residents multiplied by point HIV prevalence estimate. No. who need HIV diagnosis and no. who need HIV care = no. of HIV-positive residents minus (no. of HIV-positive residents multiplied by [point-prevalence estimates of prior HIV diagnosis and current enrollment in HIV care, respectively]). ART intervention targets were not established in 2014 because only HIV-positive persons with a CD4 count <350/μL were eligible for ART.
¶ HIV diagnosed = clients aged 15–49 years who tested HIV-positive as part of combination prevention services (October 2014–March 2017), reported never previously testing positive for HIV infection, and were referred to Bukoba Municipal Council participating health care facilities. Enrolled in HIV care = linkage case management clients aged 15–49 years confirmed by medical record to have received HIV care at least once at participating health care facilities during October 2014–May 2017. Data on clients who received a new HIV diagnosis and enrolled in HIV care were collected by government-required age group intervals: 15–24 and 25–49 years. The percentage of clients aged 15–17 years is unknown; approximately 1% of ART patients at participating facilities are aged 15–17 years.
** Percentages are of estimated HIV-positive residents in 2014.
†† Percentages are of estimated HIV-positive residents in need of HIV diagnosis in 2014. Percentages >100% indicate that more HIV-positive persons aged 18–49 years received a new HIV diagnosis than expected based on census and preintervention survey point-prevalence estimates.
§§ Percentages are of estimated HIV-positive residents in need of HIV care in 2014. Percentages >100% indicate that more HIV-positive persons aged 18–49 years were enrolled in HIV care than expected based on census and preintervention survey point-prevalence estimates.