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. Author manuscript; available in PMC: 2020 Jul 21.
Published in final edited form as: Org Biomol Chem. 2019 Jun 25;17(27):6607–6611. doi: 10.1039/c9ob01165j

Table 4.

Substrate scope for asymmetric ketone alkylationa,b,c

graphic file with name nihms-1038683-t0006.jpg
a

Reaction conditions: Pd(MeCN)2Cl2. (10 mol%), A9 (30 mol%), AcOH (1 eq.), 24 hours.

b

Isolated yield.

c

The dr and ee was determined by HPLC.

d

80 °C.