Table 1.
Demographics of patients with negative MRI who underwent prostate biopsy
| Biopsy Outcome | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall | Clinically Significant Prostate Ca* |
Clinically Insignificant Prostate Ca † |
Benign | p Value | |||||
| No. pts | 135 | 24 | 27 | 84 | – | ||||
| Median age (IQR) | 64 | (58–69) | 66 | (58–71) | 67 | (59–70) | 63 | (57–69) | 0.5 |
| Median ng/ml PSA (IQR) | 5.9 | (4.1–8.0) | 6.1 | (4.9–8.1) | 5.2 | (3.4–8.4) | 5.9 | (4.5–7.9) | 0.5 |
| Median cc prostate vol (IQR) | 55 | (38–79) | 36 | (27–50) | 43 | (34–58) | 64 | (48–81) | <0.001 |
| Median ng/ml/cc PSAD (IQR) | 0.1 | (0.073–0.15) | 0.16 | (0.13–0.20) | 0.10 | (0.09–0.15) | 0.09 | (0.07–0.12) | <0.001 |
| No. prostate Ca (%): | |||||||||
| Suspicious digital rectal examination | 11 | (8.1) | 0 | 2 | (7) | 9 | (10) | 0.3 | |
| Family history | 33 | (24) | 6 | (25) | 7 | (26) | 20 | (24) | 1.0 |
| Median No. biopsy cores/pt (IQR) | 13 | (12–14) | 13 | (12–14) | 13 | (12–14) | 13 | (12–14) | 0.4 |
| No. prostate biopsy status (%): | |||||||||
| Naïve | 48 | (36) | 10 | (42) | 8 | (30) | 30 | (36) | 0.6 |
| Previous neg | 60 | (44) | 5 | (21) | 7 | (26) | 48 | (57) | <0.001 |
| Previous pos | 27 | (20) | 9 | (38) | 12 | (44) | 6 | (7) | <0.001 |
*
Grade Group 2 or greater.
†
Grade Group 1.