Table 2.
Predictors of absent biopsy detected, clinically significant prostate cancer in men with negative MRI
| Univariate | Multivariable | ||||
|---|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | ||
| Age | 0.99 | (0.94–1.06) | 0.97 | – | – |
| PSA | 1.02 | (0.93–1.11) | 0.7 | – | – |
| Prostate vol | 1.03 | (1.01–1.06) | 0.004 | – | – |
| PSAD | 0.01 | (0.0002–0.55) | 0.02 | – | – |
| PSAD less than 0.15 ng/ml/cc | 5.93 | (2.32–15.2) | <0.001 | 7.7 (2.8–21.3) | <0.001 |
| DRE suspicious for PCa (yes vs no) | 0 (0–1.81) | 0.2 | – | – | |
| Prostate Ca family history (yes vs no) | 0.96 | (0.35–2.68) | 0.9 | – | – |
| Biopsy naïve (yes vs no) | 0.73 | (0.30–1.79) | 0.5 | – | – |
| Previous biopsy (yes vs no): | |||||
| Neg | 3.73 | (1.30–10.7) | 0.01 | 5.2 (1.6–16.5) | 0.005 |
| Pos | 0.32 | (0.12–0.85) | 0.02 | – | – |
| PI-RADS version 1 vs 2 | 0.62 | (0.24–1.56) | 0.31 | – | – |