Table 1:
Baseline Characteristics, n (%) or mean (SD) (N=137)
| Placebo (n=67) | Nicotine (n=70) | P-Value* | |
|---|---|---|---|
| Site | |||
| Baystate Medical Center | 44 (66%) | 45 (64%) | 1.000 |
| Hartford Hospital | 23 (34%) | 25 (36%) | |
| Age in Years | 28.24 (6.30) | 26.97 (5.45) | 0.257 |
| Cigarettes smoked per day | 8.04 (4.59) | 8.66 (4.71) | 0.321 |
| FTCDa score | 4.27 (2.00) | 4.25 (1.79) | 0.922 |
| Race/Ethnicity | 0.378 | ||
| Hispanic or Latino | 33 (50%) | 28 (41%) | |
| Non Hispanic, White | 25 (38%) | 26 (38%) | |
| Non Hispanic, Black | 8 (12%) | 14 (20%) | |
| Other | 0 (0%) | 1 (1%) | |
| Highest level of education completed | 0.836 | ||
| Grade school completed | 20 (30%) | 18 (26%) | |
| High school completed | 31 (46%) | 36 (51%) | |
| College or post-college completed | 16 (24%) | 16 (23%) | |
| Insurance | 0.745 | ||
| Public | 63 (94%) | 64 (91%) | |
| Private | 4 (6%) | 6 (9%) | |
| Opioid Dependence Treatment | 13 (19%) | 12 (17%) | 0.826 |
| Medical History | |||
| Depression or anxiety | 39 (58%) | 44 (63%) | 0.604 |
| Substance abuse | 23 (34%) | 26 (37%) | 0.859 |
| Progesterone use | 5 (7%) | 6 (9%) | 0.999 |
| Pregnancy | |||
| Number of previous (median) pregnancies | 2 | 2 | 0.733 |
| Gestational age at entry (week) | 17.38 (3.88) | 17.54 (3.91) | 0.880 |
| Gestational age starting inhaler use | 19.39 (4.10) | 19.73 (4.08) | 0.629 |
| History of preterm delivery | 6 (9%) | 15 (21%) | 0.057 |
| First pregnancy | 14 (21%) | 12 (17%) | 0.665 |
| Motivation to quit smoking (0–10) | 8.76 (1.53) | 8.13 (1.61) | 0.016 |
| Self-efficacy to quit smoking (0–10) | 7.54 (2.1) | 6.90 (2.37) | 0.135 |
*
Fisher’s exact test for categorical variables and Wilcoxon rank-sum test for continuous/discrete variables.
a
Fagertsrom test for nicotine dependence