Figure 8d.

Decrease in enhancement and iodine concentration in a hepatic metastasis of RCC in a 58-year-old woman after treatment with a tyrosine kinase inhibitor. (a) Baseline contrast-enhanced CT image of the upper abdomen obtained during the early arterial phase shows an avidly enhancing lesion in the right hepatic lobe (arrow), which is compatible with an RCC metastasis. (b) Contrast-enhanced CT image acquired after the initiation of pazopanib shows a decrease in enhancement in the hepatic lesion without a substantial change in size (arrow). (c, d) Iodine maps obtained before (c) and after (d) therapy show a corresponding decrease in iodine concentration (arrow).