Fig 5. Transcriptomic, proteomic and lipidomic differences between treated and untreated worms.
Differential analyses of the (A) mRNA, (B) protein and (C) lipid levels between exsheathed the third-stage larvae (xL3s) and (25S)-Δ7-DA-treated xL3s of Haemonchus contortus at 24 h following exsheathment. Molecules that were significantly up-regulated (red) or down-regulated (blue) in (25S)-Δ7-DA-treated xL3s are indicated. (D) These molecular alterations inferred to associate with cellular growth, lipid signalling, fat degradation, pharynx development and body morphogenesis; gene and protein designations derived from Caenorhabditis elegans homologues (WormBase).
