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. 2019 Jul 23;15(7):e1007960. doi: 10.1371/journal.ppat.1007960

Fig 6. Effects of dafadine A on DA biosynthesis, larval development and lipid metabolism.

Fig 6

(A) Treatment with 100 μM of dafadine A results in a reduced larval development, which is linked to (B) a significantly lower level of endogenous Δ7-DA in dafadine-treated worms. The inhibitory effect of dafadine A and rescuing effect of 1.25 μM of (25S)-Δ7-DA on (C) larval exsheathment and (D) development. An error bar indicates a standard deviation (SD; four replicates). Statistical significance is indicated with one or more asterisks (*P < 0.05, **P < 0.01, ***P < 0.001, using the Student’s t-test).