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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Acta Biomater. 2019 Apr 11;90:241–253. doi: 10.1016/j.actbio.2019.04.016

Table 3:

Comparison of fitted parameters with measurements of isolated myocytes and collagen fibers.

Description Fitted model parameters Reported Values
Cardiac muscle stiffness modulus 13.49 ± 1.92kPa* Guinea pig:16.4 ± 11.0 kpa [42];
Hamster: 7.48 ± 1.73 kpa [30];
Cardiac muscle uniaxial stress 1.36 ± 0.28 kPa* Guinea pig: 2.1 ± 1.4 kpa [42];
Hamster: 0.88 ± 0.48 kpa [30];
Collagen fiber stiffness C4 5.1 ± 1.7MPa Skin: 0 ~ 50 MPa [43]
Collagen fiber mean tortuosity 1.116** Canine: 1.01~1.2 [44]
*

Cardiac muscle stiffness and uniaxial stress were computed at 2.2 μm sarcomere length. Based on a resting sarcomere length of 1.9 μm, this translates at an engineering strain ϵ ≈ 0.158

**

The collagen fiber mean tortuosity was computed from the collagen fiber straightening strain mc by 2mc+1 where mc = 0.12