Table 3:
Comparison of fitted parameters with measurements of isolated myocytes and collagen fibers.
| Description | Fitted model parameters | Reported Values |
|---|---|---|
| Cardiac muscle stiffness modulus | 13.49 ± 1.92kPa* | Guinea pig:16.4 ± 11.0 kpa [42]; Hamster: 7.48 ± 1.73 kpa [30]; |
| Cardiac muscle uniaxial stress | 1.36 ± 0.28 kPa* | Guinea pig: 2.1 ± 1.4 kpa [42]; Hamster: 0.88 ± 0.48 kpa [30]; |
| Collagen fiber stiffness C4 | 5.1 ± 1.7MPa | Skin: 0 ~ 50 MPa [43] |
| Collagen fiber mean tortuosity | 1.116** | Canine: 1.01~1.2 [44] |
Cardiac muscle stiffness and uniaxial stress were computed at 2.2 μm sarcomere length. Based on a resting sarcomere length of 1.9 μm, this translates at an engineering strain ϵ ≈ 0.158
The collagen fiber mean tortuosity was computed from the collagen fiber straightening strain mc by where mc = 0.12