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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Mol Cancer Ther. 2019 Jun 4;18(8):1451–1459. doi: 10.1158/1535-7163.MCT-18-1125

Figure 3.

Figure 3

Messenger RNA (mRNA) transcripts which associate with the prognostic long non-coding RNA (lncRNA) score in older patients (aged ≥60 years) with cytogenetically normal acute myeloid leukemia (CN-AML). A, Heat map of the gene-expression signature associated with the lncRNA score. Rows represent protein-coding genes and columns represent patients. Patients are grouped by lncRNA score: low on the left and high on the right. The lncRNA score of each individual patient was computed as a weighted score of 46 prognostic lncRNAs. Expression values of the mRNA transcripts are represented by color: green, expression less than median value; red, expression greater than median value. B, Gene Ontology functional groups that positively correlate with high lncRNA scores in older patients with CN-AML. Gene Ontology functional groups are ranked according to fold enrichment.