Table 2.
Geometric Mean Serum PSA Concentration (ng/mL) and 95% CIs by Quintile of Fibrosis Scores Among Men 40 Years and Older, NHANES 2001–2010
| APRI | ||||||
|---|---|---|---|---|---|---|
| Q1 (<0.24) | Q2 (0.24 to <0.29) | Q3 (0.29 to <0.35) | Q4 (0.35 to <0.44) | Q5 (≥0.44) | Per 1 unit increase in fibrosis score (p trend) |
|
| Model 1a | 1.03 (0.98,1.09) | 0.96 (0.91,1.02) | 0.94 (0.89,0.99) | 0.97 (0.93,1.01) | 0.89 (0.84,0.95) | −0.36 (<0.001) |
| Model 2b | 1.04 (0.99,1.10) | 0.96 (0.91,1.02) | 0.93 (0.89,0.98) | 0.97 (0.93,1.01) | 0.89 (0.84,0.95) | −0.38 (<0.001) |
| FIB4 | ||||||
| Q1 (<0.79) | Q2 (0.79 to <0.99) | Q3 (0.99 to <1.23) | Q4 (1.23 to <1.62) | Q5 (≥1.62) | Per 1 unit increase in fibrosis score (p trend) |
|
| Model 1 | 1.03 (0.97,1.08) | 0.96 (0.92,1.01) | 0.97 (0.91,1.03) | 0.94 (0.89,0.99) | 0.90 (0.84,0.96) | −0.09 (0.007) |
| Model 2 | 1.04 (0.99,1.10) | 0.97 (0.93,1.02) | 0.97 (0.92,1.03) | 0.94 (0.89,0.99) | 0.88 (0.83,0.95) | −0.11 (0.001) |
| NFS | ||||||
| Q1 (<0.17) | Q2 (0.17 to <0.89) | Q3 (0.89 to <1.58) | Q4 (1.58 to <2.42) | Q5 (≥2.42) | Per 1 unit increase in fibrosis score (p trend) |
|
| Model 1 | 1.05 (1.00,1.11) | 0.99 (0.94,1.04) | 1.01 (0.96,1.05) | 0.92 (0.86,0.98) | 0.84 (0.78,0.91) | −0.06 (<0.001) |
| Model 2 | 1.02 (0.96,1.08) | 0.96 (0.92,1.01) | 1.00 (0.95,1.04) | 0.93 (0.87,0.99) | 0.89 (0.82,0.96) | −0.04 (0.017) |
a
Model 1 adjusted for age and race;
b
Model 2 adjusted for the age, race, BMI category, diabetes status, alcohol drinking status and smoking status.