Table 1:
Study Details and Patient Demographics
| Study | Sample Size | Age (years) | Female (%) | Intervention | Body weight Pre (kg) | Body weight Post (kg) | Follow-up (months) | Hemodynamic and Metabolic Variables Assessed |
|---|---|---|---|---|---|---|---|---|
| Alaud-din A et al 1990(17) | 12 | NA | 87 | BS | 132±17 | 77±5 | 13±4 | CO, SV, HR |
| Alexander et al, 1972(18) | 9 | 38±13 | 78 | CR | 166±31 | 111±28 | 13 (range 4–34) | PCWP, PAm, MAP, CO, SV, HR, SVR, BV, VO2, AVO2D |
| Andersson et al, 1984(16) | 10 | 51±4 | NA | CR | 98±8 | 89±9 | NA | MAP, CO, SV, HR, SVR, BV |
| Backman et al, 1979(19) | 22 | 35±2 | 77 | BS | 146±4 | 88±3 | 23 (range 10–38) | PCWP, PAm, PASP, MAP, CO, SV, HR, VO2, AVO2D |
| Kaltman et al, 1975(20) | 4 | 32±9 | 50 | CR | 155±33 | 116±17 | 4–20 | PCWP, RAP, MAP, CO, SV, HR, VO2, AVO2D, |
| Reisin et al, 1983(21) | 12 | NA | NA | CR | 96±4 | 86±4 | 9±3 | MAP, CO, SV, HR, SVR |
| Slany et al, 1974(22) | 12 | 43±13 | 58 | CR | 115±18 | 104±17 | 0.5–1 | PCWP, PAm, MAP, CO, HR, |
| Slany et al, 1975(23) | 11 | 38±9 | 79 | CR | 116±15 | NA* | 0.5–0.7 | PCWP, PAm, RAP, MAP, CO, SV, HR |
| Sugerman et al, 1988(24) | 18 | NA | NA | BS | 224±59 (%IBW) | 167±57 (%IBW) | 3–9 | PCWP, PAm |
NA indicates data not available
*
although absolute body weight post intervention was not reported in the Slany et al (1975) study, the range of weight loss was 8–15 kg; BS, bariatric surgery; CR, caloric restriction; AVO2D, arterial-venous oxygen content difference; BV, blood volume; CO, cardiac output; HR, heart rate; IBW, ideal body weight; MAP, mean arterial pressure; PAm, mean pulmonary artery pressure; PASP, pulmonary artery systolic pressure; RAP, right atrial pressure; SV, stroke volume; SVR, systemic vascular resistance; VO2, oxygen consumption.