Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 2;9:11220. doi: 10.1038/s41598-019-47551-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Comparison of the large tetanus toxin-encoding plasmids. (A) The closed plasmid pE88 of clade 1A strain E88 was used as reference. All other C. tetani genomes were searched against p88. It can be seen that all clade 1A genomes shared the same or a highly similar plasmid, except three strains (ATCC19406, 1586-Z1 and 407-86). The most outer ring depicts genes identified on pE88; important genes are highlighted in color, including tent (in pink) and colT (in light green). All other strains (subclades 1B to 1H and clade 2) carried substantial differences in their plasmids. The following references were taken: (B) the plasmid in clade 2 strain 12124569; (C) the plasmid contig in clade 2 strain 3483; (D) the plasmid contig in subclade 1G strain 132CV; (E) the plasmid contig in subclade 1B strain TMB2. Only comparisons are shown for strains, for which the plasmid sequence was present in a single contig, likely corresponding to the entire plasmid sequence.