Table 3.
Multivariate analysis of predictors of theeGFR one year after RTx in ml/min/1.73 m2 using stepwise forward selection in linear regression analysis (for details, see Methods).
| Primary Outcome 1-y-eGFR (Linear Regression) | Model 1 | Model 2 | ||
|---|---|---|---|---|
| Independent variable | B (95% CI) | P | B (95% CI) | P |
| KDPI, % | −0.338 (−0.396–−0.280) | <0.001 | — | <0.001 |
| Donor Age, years | — | −0.478 (−0.574–−0.381) | 0.006 | |
| Donor Sex (male) | N/S: 0.099 | −4.320 (−7.388–−1.251) | ||
| Recipient Age, years | N/S: 0.401 | N/S: 0.549 | ||
| Recipient Sex (male) | N/S: 0.145 | N/S: 0.255 | ||
| Recipient BMI, kg/m² | −0.759 (−1.1135–−0.383) | <0.001 | −0.797 (−1.165–−0.428) | <0.001 |
| Dialysis Vintage, months | N/S: 0.667 | N/S: 0.900 | ||
| Cold Ischemia Time, hours | N/S: 0.073 | N/S: 0.057 | ||
| Previous RTx | N/S: 0.607 | N/S: 0.466 | ||
| Current PRA% | N/S: 0.369 | N/S: 0.259 | ||
| >3 HLA-mismatches | N/S: 0.177 | N/S: 0.280 | ||
| Donor Last Serum-Creatinine | — | −3.980 (−6.294–−1.666) | 0.001 | |
| Donor BMI, kg/m² | — | N/S: 0.206 | ||
| Donor Hypertension | — | N/S: 0.362 | ||
| Donor Diabetes mellitus | — | N/S: 0.978 | ||
| Donor Death by Anoxia | — | N/S: 0.232 | ||
| Donor cerebrovascular Death | — | −5.792 (−9.137–−2.446) | 0.001 | |
| Donor Death by Head Trauma | — | N/S: 0.213 | ||
| Donor Death by CNS-Tumor | — | N/S: 0.251 | ||
| Donor Death by other cause | — | N/S: 0.768 | ||
Given are coefficients of regression (B) with 95% confidence interval (95% CI) and p-value of a likelihood-ratio test for the selected variables. For non-selected (N/S) variable p-value of the score test is displayed.