Table 4.
Multivariate analysis of predictors of death-censored allograft survivalusing stepwise forward selection in Cox regression analysis (for details, see Methods).
| Death-censored Allograft-Survival (Cox Regression) | Model 1 | Model 2 | ||
|---|---|---|---|---|
| Independent variable | HR (95% CI) | P | HR (95% CI) | P |
| KDPI, % | 1.026 (1.013–1.039) | <0.001 | — | |
| Donor Age, years | — | 1.037 (1.018–1.057) | <0.001 | |
| Donor Sex (male) | N/S: 0.155 | N/S: 0.089 | ||
| Recipient Age, years | N/S: 0.845 | N/S: 0.604 | ||
| Recipient Sex (male) | N/S: 0.723 | N/S: 0.750 | ||
| Recipient BMI, kg/m² | N/S: 0.570 | N/S: 0.578 | ||
| Dialysis Vintage, months | N/S: 0.455 | N/S: 0.561 | ||
| Cold Ischemia Time, hours | 1.066 (1.009–1.125) | 0.021 | 1.060 (1.005–1.118) | 0.032 |
| Previous RTx | N/S: 0.346 | N/S: 0.484 | ||
| Current PRA% | N/S: 0.752 | N/S: 0.653 | ||
| >3 HLA-mismatches | N/S: 0.927 | N/S: 0.785 | ||
| Donor Last Serum-Creatinine | — | N/S: 0.488 | ||
| Donor BMI, kg/m² | — | N/S: 0.541 | ||
| Donor Hypertension | — | N/S: 0.747 | ||
| Donor Diabetes mellitus | — | N/S: 0.732 | ||
| Donor Death by Anoxia | — | N/S: 0.981 | ||
| Donor cerebrovascular Death | — | N/S: 0.274 | ||
| Donor Death by Head Trauma | — | N/S: 0.172 | ||
| Donor Death by CNS-Tumor | — | N/S: 0.564 | ||
| Donor Death by other cause | — | N/S: 0.930 | ||
Given are hazard ratios (HR) with 95% confidenceinterval (95% CI) and p-value of a likelihood-ratio test for the selected variables. For non-selected (N/S) variable p-value of the score test is displayed.