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. 2019 Feb 28;15(2):104–115. doi: 10.6026/97320630015104

Table 4. Drug-drug comparative study result.

Established Drug Virtual Screened Drug
Energy overview: Descriptors MolDock Score Rerank Score MolDock Score Re-rank Score
Total Energy -209.504 -172.881 -230.32 -187.558
External Ligand interactions -230.614 -199.032 -251.6 -217.967
Protein - Ligand interactions -230.614 -199.032 -251.6 -217.967
Steric (by PLP) -225.723 -154.846 -245.115 -168.149
Steric (by LJ12-6) -40.313 -44.681
Hydrogen bonds -4.891 -3.874 -6.485 -5.136
Internal Ligand interactions 21.109 26.152 21.28 30.409
Torsional strain 8.82 8.273 13.933 13.069
Torsional strain (sp2-sp2) 2.713 3.379
Hydrogen bonds 0 0
Steric (by PLP) 12.672 2.18 7.723 1.328
Steric (by LJ12-6) 12.986 12.632