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. 2019 Feb 28;15(2):139–150. doi: 10.6026/97320630015139

Table . Drug-Drug comparative study.

Virtual Screened Drug CID: 127263272 Established drug CID:117951478
Energy overview: Descriptors MolDock Score Rerank Score MolDock Score Rerank Score
Total Energy -193.236 -151.724 -200.215 -161.944
External Ligand interactions -225.405 -188.661 -226.851 -191.146
Protein - Ligand interactions -225.405 -188.661 -226.851 -191.146
Steric (by PLP) -220.879 -151.523 -221.615 -152.028
Steric (by LJ12-6) -33.554 -34.971
Hydrogen bonds -4.526 -3.584 -5.236 -4.147
Internal Ligand interactions 32.169 36.937 26.636 29.202
Torsional strain 20.749 19.463 12.76 11.969
Torsional strain (sp2-sp2) 3.801 3.798
Hydrogen bonds 0 0
Steric (by PLP) 11.42 1.964 13.876 2.387
Steric (by LJ12-6) 11.71 11.048