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. 2019 Feb 28;15(2):139–150. doi: 10.6026/97320630015139

Table 7. ADMET Predicted Profile (regression analysis).

PD1-PDL1 inhibitor Established drug CID:117951478 XGIQBUNWFCCMAS-UHFFFAOYSA-N Virtual Screened Drug CID: 127263272
Model Absorption Unit Value Value
Aqueous solubility LogS -2.3186 -2.7996
Caco-2 Permeability LogPapp, cm/s 1.1475 1.212
Toxicity
Rat Acute Toxicity LD50, mol/kg 2.4295 2.5248
Fish Toxicity pLC50, mg/L 1.6327 1.4204
Tetrahymena Pyriformis Toxicity pIGC50, ug/L 0.3436 0.4986