Table 1. Absolute and normalized distribution of acidic and basic residues of protein and that participates in the SB formation. hsMDH and ecMDH has 303 and 312 residues respectively. Thus, frequency of these residues of hsMDH is first scaled to, per 312 residues. Now for protein (P), the total absolute frequency is referenced to 100 and then, frequencies of protein surface (P su), protein core (P co) and SB total are computed. Normalization of SB su and SB co are done using absolute frequency of SB total as reference.
| ASP | GLU | HIS | ARG | LYS | ||||||
| ecMDH | hsMDH | ecMDH | hsMDH | ecMDH | hsMDH | ecMDH | hsMDH | ecMDH | hsMDH | |
| P total | 12 (100) | 35 (100) | 20 (100) | 24.7 (100) | 2 (100) | 6.2 (100) | 8 (100) | 13.4 (100) | 21 (100) | 7.2 (100) |
| P su | 10 (83.3) | 31.9 (91.2) | 16 (80) | 21.6 (87.5) | 1 (50) | 4.1 (66.7) | 7 (87.5) | 8.2 (61.5) | 18 (85.7) | 6.2 (85.7) |
| P co | 2 (16.7) | 3.1 (8.8) | 4 (20) | 3.1 (12.5) | 1 (50) | 2.1 (33.3) | 1 (12.5) | 5.1 (38.5) | 3 (14.3) | 1 (14.3) |
| SB total | 4 (33.3) | 11.3 (32.4) | 11 (55) | 13.4 (54.2) | 1 (50) | 4.1 (66.7) | 7 (87.5) | 13.4 (100) | 7 (33.3) | 7.2 (100) |
| SB su | 2 (16.7) | 8.2 (23.5) | 7 (35) | 10.3 (41.7) | 0 (0) | 2.1 (33.3) | 6 (75) | 8.2 (61.5) | 7 (33.3) | 6.2 (85.7) |
| SB co | 2 (16.7 ) | 3.1 (8.8) | 4 (20) | 3.1 (12.5) | 1 (50) | 2.1 (33.3) | 1 (12.5) | 5.1 (38.5) | 0 (0) | 1 (14.3) |