Table 2.
Gene | FEP vs HC | Scz vs HC | OP vs HC | Chr |
---|---|---|---|---|
Top 50 Up-regulated - logFC (q-value) | ||||
CAMP | 0.66 (<0.001) | 0.94 (<0.001) | 0.38 (0.058) | 3 |
DEFA1B | 0.97 (<0.001) | 1.25 (<0.001) | 0.69 (0.042) | 8 |
DEFA3 | 0.95 (<0.001) | 1.24 (<0.001) | 0.66 (0.046) | 8 |
DEFA1 | 0.87 (<0.001) | 1.1 (<0.001) | 0.64 (0.041) | 8 |
C9ORF72 | 0.24 (<0.001) | 0.3 (<0.001) | 0.19 (0.041) | 9 |
CLNS1A | 0.18 (<0.001) | 0.23 (<0.001) | 0.13 (0.049) | 11 |
SUMO3 | 0.11 (<0.001) | 0.12 (<0.001) | 0.1 (0.022) | 21 |
TMEM170B | 0.3 (<0.001) | 0.36 (<0.001) | 0.25 (0.037) | 6 |
PSMC2 | 0.14 (<0.001) | 0.18 (<0.001) | 0.1 (0.050) | 7 |
HBXIP | 0.1 (<0.001) | 0.13 (<0.001) | 0.07 (0.053) | 1 |
PARL | 0.1 (<0.001) | 0.12 (<0.001) | 0.07 (0.048) | 3 |
IFNGR1 | 0.16 (<0.001) | 0.19 (<0.001) | 0.12 (0.050) | 6 |
GLRX | 0.24 (<0.001) | 0.29 (<0.001) | 0.19 (0.042) | 5 |
IDH1 | 0.14 (<0.001) | 0.16 (<0.001) | 0.12 (0.036) | 2 |
TCEB1 | 0.14 (<0.001) | 0.16 (<0.001) | 0.11 (0.041) | 8 |
CCPG1 | 0.17 (<0.001) | 0.21 (<0.001) | 0.13 (0.046) | 15 |
LYPLAL1 | 0.18 (<0.001) | 0.2 (<0.001) | 0.16 (0.037) | 1 |
SLC30A9 | 0.18 (<0.001) | 0.2 (<0.001) | 0.15 (0.037) | 4 |
TMBIM4 | 0.08 (<0.001) | 0.1 (<0.001) | 0.07 (0.044) | 12 |
FAM96A | 0.25 (<0.001) | 0.29 (<0.001) | 0.2 (0.040) | 15 |
FAM45A | 0.13 (<0.001) | 0.16 (<0.001) | 0.1 (0.048) | 10 |
GNG10 | 0.31 (<0.001) | 0.39 (<0.001) | 0.24 (0.053) | 9 |
C14ORF100 | 0.15 (<0.001) | 0.17 (<0.001) | 0.12 (0.040) | 14 |
COX7A2 | 0.22 (<0.001) | 0.27 (<0.001) | 0.18 (0.046) | 6 |
TAF7 | 0.2 (<0.001) | 0.24 (<0.001) | 0.17 (0.040) | 5 |
MAP2K1IP1 | 0.21 (<0.001) | 0.25 (<0.001) | 0.17 (0.046) | 4 |
CRLS1 | 0.21 (<0.001) | 0.24 (<0.001) | 0.17 (0.041) | 20 |
COX7A2L | 0.19 (<0.001) | 0.21 (<0.001) | 0.16 (0.037) | 2 |
ATP5C1 | 0.24 (<0.001) | 0.29 (<0.001) | 0.2 (0.045) | 10 |
FBXL5 | 0.13 (<0.001) | 0.15 (<0.001) | 0.1 (0.049) | 4 |
UQCRQ | 0.28 (<0.001) | 0.33 (<0.001) | 0.23 (0.046) | 5 |
BNIP2 | 0.18 (<0.001) | 0.19 (<0.001) | 0.16 (0.037) | 15 |
SLC35A1 | 0.19 (<0.001) | 0.23 (<0.001) | 0.15 (0.059) | 6 |
RPSA | 0.16 (<0.001) | 0.2 (<0.001) | 0.12 (0.061) | 3 |
LYST | 0.14 (<0.001) | 0.16 (<0.001) | 0.12 (0.046) | 1 |
WDR61 | 0.13 (<0.001) | 0.16 (<0.001) | 0.11 (0.044) | 15 |
SRP9 | 0.2 (<0.001) | 0.22 (<0.001) | 0.18 (0.038) | 1 |
VBP1 | 0.22 (<0.001) | 0.25 (<0.001) | 0.19 (0.041) | X |
PCMT1 | 0.14 (<0.001) | 0.14 (<0.001) | 0.13 (0.036) | 6 |
TMX1 | 0.25 (<0.001) | 0.29 (<0.001) | 0.2 (0.048) | 14 |
SLC44A1 | 0.18 (<0.001) | 0.19 (<0.001) | 0.16 (0.036) | 9 |
PRDX3 | 0.13 (<0.001) | 0.14 (<0.001) | 0.12 (0.037) | 10 |
COX17 | 0.13 (<0.001) | 0.15 (<0.001) | 0.11 (0.042) | 3 |
KIAA1600 | 0.19 (<0.001) | 0.22 (<0.001) | 0.15 (0.050) | 10 |
PIGY | 0.17 (<0.001) | 0.2 (<0.001) | 0.15 (0.044) | 4 |
COMMD3 | 0.17 (<0.001) | 0.21 (<0.001) | 0.14 (0.049) | 10 |
KBTBD11 | 0.16 (<0.001) | 0.19 (<0.001) | 0.13 (0.050) | 8 |
TMEM14B | 0.16 (<0.001) | 0.19 (<0.001) | 0.13 (0.055) | 6 |
VAMP7 | 0.15 (<0.001) | 0.16 (<0.001) | 0.14 (0.036) | XY |
LDHA | 0.11 (<0.001) | 0.11 (<0.001) | 0.11 (0.036) | 11 |
Top 50 Down-regulated - logFC (q-value) | ||||
RBM14 | −0.13 (<0.001) | −0.17 (<0.001) | −0.09 (0.046) | 11 |
HNRNPUL2 | −0.19 (<0.001) | −0.23 (<0.001) | −0.14 (0.040) | 11 |
GABPB2 | −0.09 (<0.001) | −0.11 (<0.001) | −0.06 (0.053) | 1 |
FAM110A | −0.16 (<0.001) | −0.19 (<0.001) | −0.12 (0.046) | 20 |
SCAP | −0.14 (<0.001) | −0.17 (<0.001) | −0.11 (0.046) | 3 |
PNPT1 | −0.11 (<0.001) | −0.14 (<0.001) | −0.08 (0.050) | 2 |
RASGRP2 | −0.12 (<0.001) | −0.15 (<0.001) | −0.09 (0.050) | 11 |
ZC3H5 | −0.11 (<0.001) | −0.13 (<0.001) | −0.08 (0.057) | |
TMEM69 | −0.11 (<0.001) | −0.13 (<0.001) | −0.1 (0.037) | 1 |
CLSTN1 | −0.16 (<0.001) | −0.2 (<0.001) | −0.12 (0.058) | 1 |
GANAB | −0.12 (<0.001) | −0.15 (<0.001) | −0.09 (0.054) | 11 |
DENND4B | −0.12 (<0.001) | −0.14 (<0.001) | −0.09 (0.046) | 1 |
ZNF296 | −0.16 (<0.001) | −0.19 (<0.001) | −0.13 (0.042) | 19 |
KIAA1267 | −0.1 (<0.001) | −0.13 (<0.001) | −0.08 (0.051) | 17 |
CXXC1 | −0.12 (<0.001) | −0.14 (<0.001) | −0.1 (0.046) | 18 |
POM121C | −0.13 (<0.001) | −0.16 (<0.001) | −0.1 (0.049) | 7 |
RANGAP1 | −0.12 (<0.001) | −0.15 (<0.001) | −0.1 (0.050) | 22 |
STIP1 | −0.14 (<0.001) | −0.17 (<0.001) | −0.1 (0.060) | 11 |
ITPKB | −0.13 (<0.001) | −0.16 (<0.001) | −0.1 (0.055) | 1 |
CD97 | −0.16 (<0.001) | −0.2 (<0.001) | −0.13 (0.053) | 19 |
HGS | −0.1 (<0.001) | −0.13 (<0.001) | −0.08 (0.060) | 17 |
SUPT5H | −0.14 (<0.001) | −0.16 (<0.001) | −0.11 (0.042) | 19 |
UBQLN4 | −0.12 (<0.001) | −0.14 (<0.001) | −0.1 (0.044) | 1 |
SPG7 | −0.11 (<0.001) | −0.13 (<0.001) | −0.08 (0.058) | 16 |
RAB11FIP1 | −0.14 (<0.001) | −0.16 (<0.001) | −0.12 (0.046) | 8 |
TRIM28 | −0.14 (<0.001) | −0.16 (<0.001) | −0.11 (0.053) | 19 |
WDR23 | −0.12 (<0.001) | −0.13 (<0.001) | −0.1 (0.041) | 14 |
GPS1 | −0.09 (<0.001) | −0.1 (<0.001) | −0.08 (0.046) | 17 |
FBXO46 | −0.16 (<0.001) | −0.18 (<0.001) | −0.15 (0.041) | 19 |
TLN1 | −0.21 (<0.001) | −0.24 (<0.001) | −0.18 (0.044) | 9 |
ABCF1 | −0.11 (<0.001) | −0.13 (0.001) | −0.09 (0.060) | 6 |
ORC6L | −0.1 (<0.001) | −0.11 (0.001) | −0.08 (0.046) | 16 |
UBA1 | −0.17 (<0.001) | −0.2 (0.001) | −0.13 (0.061) | X |
SRRM2 | −0.11 (<0.001) | −0.14 (0.001) | −0.09 (0.057) | 16 |
PDPR | −0.21 (<0.001) | −0.24 (0.001) | −0.18 (0.047) | |
XRCC6 | −0.13 (<0.001) | −0.14 (0.001) | −0.11 (0.046) | 22 |
LBA1 | −0.18 (<0.001) | −0.21 (0.001) | −0.16 (0.048) | 3 |
GCN1L1 | −0.12 (<0.001) | −0.14 (0.001) | −0.1 (0.052) | 12 |
C21ORF58 | −0.12 (<0.001) | −0.14 (0.002) | −0.1 (0.061) | 21 |
EMD | −0.09 (<0.001) | −0.1 (0.002) | −0.07 (0.059) | X |
ST3GAL1 | −0.14 (<0.001) | −0.15 (0.002) | −0.13 (0.037) | 8 |
TSSC4 | −0.11 (<0.001) | −0.11 (0.002) | −0.1 (0.037) | 11 |
EDC4 | −0.1 (<0.001) | −0.11 (0.002) | −0.1 (0.037) | 16 |
CORO7 | −0.12 (<0.001) | −0.14 (0.002) | −0.11 (0.048) | 16 |
WASF2 | −0.18 (<0.001) | −0.2 (0.002) | −0.17 (0.040) | 1 |
UBA52 | −0.11 (<0.001) | −0.12 (0.002) | −0.1 (0.044) | 19 |
NRGN | −0.3 (<0.001) | −0.33 (0.002) | −0.26 (0.048) | 11 |
AP1G2 | −0.11 (<0.001) | −0.11 (0.002) | −0.1 (0.041) | 14 |
KPNA6 | −0.12 (0.001) | −0.14 (0.002) | −0.1 (0.057) | 1 |
PBX2 | −0.12 (<0.001) | −0.13 (0.002) | −0.11 (0.041) | 6 |
Table of logFC and q-value of top up and down regulated probes for 3 comparisons (FEP vs HC, SCZ vs HC and OP vs HC) following differential expression analysis. Each comparison contains the logFC value followed by the q-value in brackets. Genes were included if the FDR adjusted q-value was less than 0.05 and the absolute log fold change was above 0.1 in all 3 comparisons. For a complete list of probes see supplementary table 2.
Table of logFC and q-value of top up and down regulated probes for 3 comparisons (FEP vs HC, SCZ vs HC and OP vs HC) following differential expression analysis. Each comparison contains the logFC value followed by the q-value in brackets. Genes were included if the FDR adjusted q-value was less than 0.05 and the absolute log fold change was above 0.1 in all 3 comparisons. For a complete list of probes see supplementary table 2.