Table 3.
Laboratory parameters of 100 children with SCA and 100 Hb AA controls
| Laboratory parameter | SCA subjects, median (IQR) | Hb AA controls, median (IQR) | Test statistica | p-Value |
|---|---|---|---|---|
| LDH level (IU/l) | 806.00 (643.5–886.3) | 493.00 (345.0–677.5) | −6.68 | <0.0001* |
| Platelet count (×109/l) | 371.00 (257.0–467.5) | 286.00 (240.8–335.5) | −4.03 | <0.0001* |
| Haematocrit (%) | 22.45 (20.2–24.4) | 33.20 (31.2–36.6) | −11.78 | <0.0001* |
| Total WBC count (×109/l) | 13.35 (10.5–16.1) | 6.20 (5.2–7.3) | −11.17 | <0.0001* |
| Reticulocyte count (×109/l) | 11.00 (8.0–15.6) | 1.80 (1.1–2.1) | −11.95 | <0.0001* |
| HbF level (%) | 9.20 (5.0–14.4) | 0.60 (0.4–1.0) | −12.01 | <0.0001* |
| Lymphocyte count (×109/l) | 6.25 (4.4–7.8) | 3.40 (2.7–4.0) | −9.42 | <0.0001* |
| Granulocyte count (×109/l) | 5.65 (4.3–7.7) | 2.50 (1.8–3.2) | −10.69 | <0.0001* |
IU/l: international units per litre.
aMann–Whitney U test.
*Statistically significant.