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. 2019 Jul 29;9(7):e027013. doi: 10.1136/bmjopen-2018-027013

Table 2.

Comparison of variables between participants with both baseline and 6-month follow-up values

Domain Data available n= Baseline 6-month follow-up P value
Falls risk
 Fear of falling, n (%) 40 0.10
    None/mild (1–2) 8.0 (20.0) 14.0 (35.0)
    Moderate (3) 24.0 (60.0) 19.0 (47.5)
    High (4) 8.0 (20.0) 7.0 (17.5)
 Risk factors for falls
    Orthostatic hypotension 104 24 (23.1) 12 (11.5) 0.002
    Depression 102 18 (17.7) 12 (11.8) 0.07
    Proprioceptive* 103 86 (83.5) 85 (82.5) 1.00
    Dizziness 103 26 (25.2) 18 (17.5) 0.06
    Vasovagal symptoms or signs 100 8 (8.0) 1 (1.0) 0.02
    Visual impairment 104 94 (90.4) 100 (96.2) 0.03
    Hearing impairment 101 64 (63.4) 63 (62.4) 1.00
    Malnutrition risk 101 26 (25.7) 25 (24.8) 1.00
Sarcopenia
  Met criteria, n (%) 105 83.0 (78.3) 79.0 (74.5) 0.51
Biochemical measures (IQR)
  Albumin (g/L) 54 43 (41–45) 42 (40–44) 0.046
  Corrected calcium (mmol/L) 41 2.4 (2.3–2.4) 2.4 (2.3–2.4) 0.31
  Creatinine (nmol/L) 54 80 (70–90) 80 (70–95) 0.46
  eGFR (mL/min) 54 65.5 (56, 78) 64 (54–82) 0.22
  Hb (g/L) 53 132 (126–142) 132 (127–143) 0.30
  Vitamin D (nmol/L) 51 63 (48–78) 65 (54–83) 0.32
  PTH (pmol/L) 43 6.9 (4.2–9.5) 6.6 (4.7–10.8) 0.48
  TSH (mlU/L) 44 1.5 (0.9–2.0) 1.6 (0.8–2.1) 0.15

Bold p values indicate significant difference between baseline and 6-month follow-up measures.

*Proprioceptive and vestibular abnormalities.

Sarcopenia criterion is fulfilling at least two of the following criteria: gait velocity <0.8 m/s, grip strength <20 kg (females) and <30 kg (males) and appendicular lean mass/height2<5.5 kg/m2 (females) or <7.26 kg/m2 (males).

BMD, bone mineral density (femoral neck); eGFR, estimated glomerular filtration rate; Hb, haemoglobin; PTH, parathyroid hormone; TSH, thyroid-stimulating hormone.