Table 2.
Follow-up mean costs (£) per patient by trial arm
| Year 1 Mean cost |
Year 2 Mean cost |
Year 3 Mean cost |
Year 4 Mean cost |
Year 5 Mean cost |
Total at year 5 | Difference (95% CI to P values) |
|||||||
| SITA (n=1554) |
BITA (n=1548) |
SITA (n=1554) |
BITA (n=1548) |
SITA (n=1554) |
BITA (n=1548) |
SITA (n=1554) |
BITA (n=1548) |
SITA (n=1554) |
BITA (n=1548) |
SITA (n=1554) |
BITA (n=1548) |
BITA vs SITA | |
| Healthcare contacts | |||||||||||||
| GP visits | 240 | 234 | 166 | 162 | 156 | 153 | 150 | 142 | 143 | 140 | 855 | 831 | −23.7 (−70 to 23; 0.319) |
| Nurse visits | 46 | 50 | 17 | 20 | 20 | 21 | 20 | 22 | 20 | 21 | 122 | 133 | 11.3 (−6 to 29; 0.203) |
| Outpatient clinic visits | 247 | 309 | 153 | 187 | 124 | 167 | 158 | 148 | 142 | 145 | 822 | 955 | 133.2 (−7 to 273; 0.062) |
| Cardiac rehabilitation visits | 370 | 378 | 84 | 82 | 63 | 50 | 49 | 70 | 39 | 39 | 606 | 619 | 13.3 (−112 to 139; 0.835) |
| Number of nights in hospital | 168 | 234 | 87 | 53 | 44 | 81 | 67 | 64 | 106 | 76 | 472 | 509 | 36.8 (−94 to 167; 0.581) |
| All healthcare contacts | 1071 | 1205 | 506 | 504 | 407 | 473 | 444 | 446 | 450 | 422 | 2877 | 3048 | 170.9 (−78 to 420; 0.178) |
| Medications | |||||||||||||
| Total medication | 37 | 38 | 39 | 41 | 40 | 44 | 41 | 45 | 41 | 43 | 198 | 211 | 13.0 (−9 to 34; 0.237) |
| Adverse event treatment | |||||||||||||
| Myocardial infarction | 15 | 12 | 3 | 5 | 6 | 9 | 7 | 6 | 9 | 9 | 40 | 41 | 1.5 (−21 to 24; 0.897) |
| Cerebrovascular accident | 26 | 13 | 12 | 12 | 10 | 7 | 7 | 10 | 21 | 16 | 76 | 57 | −18.1 (−52 to 16; 0.300) |
| Further CABG | 0 | 6 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 13 | 12.7 (−5 to 30; 0.156) |
| Further PCI | 54 | 41 | 43 | 24 | 41 | 41 | 17 | 32 | 34 | 29 | 189 | 167 | −22.0 (−86 to 42; 0.501) |
| Revascularisation with catheter | 4 | 18 | 16 | 20 | 27 | 14 | 18 | 11 | 2 | 18 | 67 | 79 | 12.7 (−22 to 47; 0.471) |
| Sternal wound problems | 104 | 295 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 105 | 296 | 191.1 (66 to 317; 0.003) |
| Major bleed | 58 | 83 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 58 | 84 | 26.1 (−64 to 116; 0.570) |
| Other events (cost of hospital stay only) | 459 | 500 | 191 | 170 | 168 | 152 | 161 | 189 | 225 | 181 | 1204 | 1192 | −12.1 (−344 to 320; 0.943) |
| Death (cost of hospital stay only) | 58 | 26 | 34 | 19 | 5 | 40 | 55 | 10 | 30 | 34 | 182 | 128 | −53.7 (−168 to 60; 0.357) |
| All adverse event costs | 777 | 994 | 299 | 249 | 258 | 269 | 266 | 259 | 320 | 286 | 1920 | 2058 | 138.3 (−283 to 559; 0.520) |
| All costs | 1848 | 2199 | 805 | 753 | 664 | 741 | 709 | 705 | 770 | 708 | 4995 | 5317 | 322.1 (−207 to 852; 0.233) |
| Difference in costs (p value) | 351 (0.028) | −52 (0.469) | 77 (0.259) | −4 (0.952) | −63 (0.561) | ||||||||
SITA, single internal thoracic artery; BITA, bilateral internal thoracic artery; CABG, coronary artery bypass graft surgery; GP, general practitioner; PCI, percutaneous coronary interventions.