Table 1.
The affinities for serotonin/dopamine receptors of the compounds 1–4.
Cpd | Ki (nM) | ||||
---|---|---|---|---|---|
5-HT6 [3H]-LSD |
D2L [3H]- Raclopride |
5-HT1A [3H]-8-OH-DPAT |
5-HT2A [3H]- Ketanserin |
5-HT7 [3H]-5-CT |
|
1 | 28 a | 838 a | 4954 a | 272 | 8710 a |
2 | 29 a | 1192 a | 10,220 a | 329 | 16,160 a |
3 | 22 a | 1946 a | 9453 a | 1757 | 16,790 a |
4 | 11 a | 1094 | 12,530 | 430 | 11,950 |