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. 2019 Jul 23;20(14):3590. doi: 10.3390/ijms20143590
TAD transactivation domain
DBD DNA binding domain
OD oligomerization domain
SAM sterile alpha motif
TID transcriptional inhibitory domain
WT wild type
HNSCC head and neck squamous cell carcinoma
miRNA microRNA
lncRNA long non-coding RNA
SA-β-gal senescence-associated β-galactosidase
HDAC histone deacetylase
BMP bone morphogenetic protein
SHH sonic hedgehog
FGFR2 fibroblast growth factor receptor 2
TGF-β transforming growth factor β
EDC epidermal differentiation complex
EEC Ectrodactyly Ectodermal Dysplasia-Clefting Syndrome
AEC Ankyloblepharon-Ectodermal Dysplasia Clefting Syndrome
SCC squamous cell carcinoma
TCGA The Cancer Genome Atlas
cSCC cutaneous squamous cell carcinoma
ChIP-Seq chromatin immunoprecipitation-sequencing
EGFR epidermal growth factor receptor
MAPK mitogen-activated protein kinase
FGF fibroblast growth factor
EMT epithelial-mesenchymal transition
iASPP inhibitor of apoptosis-stimulating protein of p53
CSC cancer stem cell
HK2 hexokinase 2
ROS reactive oxygen species
GPX2 glutathione peroxidase 2
PAI-2 plasminogen activator inhibitor-2
TIMP tissue inhibitor of metalloproteinase
MT1-MMP membrane-type 1-matrix metalloproteinase
MMP matrix metalloproteinase