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. 2019 Jul 17;11(7):994. doi: 10.3390/cancers11070994

Figure 1.

Figure 1

Simvastatin treatment induces significant cell death in medulloblastoma cells. Cell viability assays of Daoy (A), D283 (B), and D341 (C) cells, using dose-dependent analysis by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), performed every 24 h until 96 h (24 h, 48 h, 72 h, and 96 h). Medulloblastoma cells were treated with 0.5–20 µM simvastatin. Statistical significance is reported by one-way ANOVA using GraphPad Prism 7.0. The p-value is reported as **** p < 0.0001, *** p < 0.001, ** p < 0.01, or * p < 0.05. Data are expressed as means ±  SEM, and n = 15–20.