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. 2019 Jul 19;8(7):746. doi: 10.3390/cells8070746

Figure 4.

Figure 4

The effect of roscovitine on NFκB-S276 phosphorylation in microglia and monocyte following SE. NFκB-S276 phosphorylation is apparently increased in most of resident IB4 microglia and CD68 cells following SE, while it is rarely observed in control animals. Roscovitine does not affect p65 NFκB-S276 phosphorylation in resident IB4 microglia and CD68 cells (A,B) Representative images for NFκB-S276 phosphorylation in IB4 microglia and CD68 cells, respectively. (C) Quantification of the effect of roscovitine on NFκB-S276 phosphorylation in IB4 microglia and CD68 cells following SE. Error bars indicate SEM (* p < 0.05 vs. vehicle-treated animals; n = 7, respectively).