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. 2019 Jul 19;8(7):749. doi: 10.3390/cells8070749

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cellular processes compromised by methylglyoxal (MGO) and aging. MGO accumulation fosters some aging-related molecular events that are schematically reported in the figure. AGE: advanced glycation end products; MGdG: 3’-(2’-deoxyribosyl)-6,7-dihydro-6,7-dihydroxy-6-methylimidazo-[2,3-b]purine-9(8)one; RAGE: advanced glycation end products receptor.