Table 3.
Top 20 KEGG pathways significantly enriched by DEGs in TpA versus TpM.
| KEGG pathway | Pathway ID | DEGs No. | p-value |
|---|---|---|---|
| ECM-receptor interaction | ko04512 | 10 | 8.61 × 10−7 |
| Vasopressin-regulated water reabsorption | ko04962 | 8 | 2.15 × 10−6 |
| Neuroactive ligand-receptor interaction | ko04080 | 12 | 9.20 × 10−5 |
| Phagosome | ko04145 | 26 | 6.38 × 10−4 |
| MAPK signaling pathway | ko04010 | 12 | 9.15 × 10−4 |
| Sphingolipid metabolism | ko00600 | 8 | 9.92 × 10−4 |
| Fructose and mannose metabolism | ko00051 | 14 | 1.08 × 10−3 |
| Estrogen signaling pathway | ko04915 | 8 | 2.68 × 10−3 |
| Fanconi anemia pathway | ko03460 | 9 | 3.32 × 10−3 |
| Nicotinate and nicotinamide metabolism | ko00760 | 7 | 3.63 × 10−3 |
| Lysosome | ko04142 | 19 | 4.17 × 10−3 |
| Morphine addiction | ko05032 | 3 | 4.62 × 10−3 |
| Folate biosynthesis | ko00790 | 5 | 5.99 × 10−3 |
| Wnt signaling pathway | ko04310 | 19 | 5.99 × 10−3 |
| Platelet activation | ko04611 | 4 | 6.61 × 10−3 |
| Glutathione metabolism | ko00480 | 13 | 8.78 × 10−3 |
| Fatty acid biosynthesis | ko00061 | 6 | 9.19 × 10−3 |
| Gap junction | ko04540 | 9 | 1.00 × 10−2 |
| Galactose metabolism | ko00052 | 10 | 1.00 × 10−2 |
| Melanogenesis | ko04916 | 8 | 1.11 × 10−2 |
DEGs No.: Number of DEGs mapped into each KEGG pathway.