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. 2019 Jul 16;11(7):992. doi: 10.3390/cancers11070992

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Role of IL-6 in patients with prostate cancer. (a) CD44 level was positively correlated with IL-6 expression in human prostate cancer specimens (p < 0.001). Representative slides of tumor specimens positively or negative staining for IL-6 and CD44 are shown. Scale bars: 60 μm. (b) IL-6 levels measured using ELISA in serum from cancer patients with IL-6 negative and positive staining. The value indicated the median. (c) IL-6 levels measured using ELISA in serum from cancer patients with clinical localized stage or advanced stage. (d) The differences of biochemical failure-free survival according to clinical stage and the staining of IL-6 in patients with prostate cancers.