Table 1.
HLA-DQ and HLA-DR genotype and phenotype of T1D patients enrolled in the study.
| Code | Cells a | Diagnosis | DQA1 Genotype | DQB1 Genotype | DQ Phenotype | DR Phenotype |
|---|---|---|---|---|---|---|
| §1 | B-LCL | T1D | *03/*05 | *02/*03 | DQ2.5/DQ8 | DR3/DR4 |
| §2 | B-LCL | T1D | *03/*05 | *02/*02 | DQ2.5/DQ2.3 | DR3/DR9 |
| §3 | B-LCL | T1D | *05/*05 | *02/*02 | DQ2.5/DQ2.5 | DR3/DR3 |
| §4 | B-LCL | T1D with CD | *03/*05 | *02/*03 | DQ2.5/DQ8 | DR3/DR4 |
| §5 | B-LCL | T1D with CD | *01/*03 | *05/*03 | DQ8/DQ5 | DR4/DR16 |
| §6 | B-LCL | T1D with CD | *01/*05 | *02/*05 | DQ2.5/DQ5 | DR1/DR3 |
| §7 | B-LCL | T1D with CD | *02/*05 | *02/*02 | DQ2.5/DQ2.2 | DR3/DR7 |
| §8 | B-LCL | T1D with CD | *05/*05 | *02/*02 | DQ2.5/DQ2.5 | DR3/DR3 |
| §9 | PBMC | T1D | *01/*05 | *02/*05 | DQ2.5/DQ5 | DR1/DR3 |
| §10 | PBMC | T1D | *01/*05 | *02/*06 | DQ2.5/DQ6 | DR3/DR15 |
| §11 | PBMC | T1D | *01/*05 | *02/*05 | DQ2.5/DQ5 | DR1/DR3 |
| §12 | PBMC | T1D | *01/*03 | *03/*05 | DQ8/DQ5 | DR4/DR1 |
| §13 | PBMC | T1D | *03/*05 | *02/*03 | DQ2.5/DQ8 | DR3/DR4 |
| §14 | PBMC | T1D | *03/*05 | *02/*03 | DQ2.5/DQ8 | DR3/DR4 |
| §15 | PBMC | T1D | *01/*03 | *03/*05 | DQ8/DQ5 | DR4/DR1 |
| §16 | PBMC | T1D | *05/*05 | *02/*03 | DQ2.5/DQ7 | DR3/DR5 |
| §17 | PBMC | T1D | *01/*05 | *02/*05 | DQ2.5/DQ5 | DR3/DR1 |
| §18 | PBMC | T1D | *03/*03 | *03/*03 | DQ8/DQ8 | DR4/DR4 |
| §19 | PBMC | T1D | *01/*03 | *03/*05 | DQ8/DQ5 | DR4/DR1 |
| §20 | PBMC | T1D | *03/*03 | *03/*03 | DQ8/DQ8 | DR4/DR4 |
| §21 | PBMC | T1D | *01/*03 | *03/*05 | DQ8/DQ5 | DR4/DR1 |
a the immune cell source for HLA genotyping.