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. 2019 Jun 26;8(7):640. doi: 10.3390/cells8070640

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© 2019 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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ON alpha RGCs showed decreased responses to defocused image after gap junction blocker application. A: ON alpha transient RGCs showed a significantly decreased response (the probability of spikes) to plus and minus defocused images two minutes after gap junction antagonist, 25 µM 18-β application. The cell showed no response to plus and minus defocused images above 20D (black and red triangle). B: ON alpha sustained RGCs showed no response to plus and minus defocused images at +16D and -20D (black triangle). Five minutes after 25 µM 18-β application, the cells showed no response to defocused image at +5D and −15D (red triangle).