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. 2019 Jul 9;8(7):689. doi: 10.3390/cells8070689

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Arachidonic acid (AA) metabolism is not necessary for arachidonic acid-induced elevation in [Ca²⁺]_i in hCMEC/D3 cells. (A) 30 μM eicosatetraynoic acid (ETYA), a non-metabolizable analogue of AA, elicits an intracellular Ca²⁺ signal which overlaps with the Ca²⁺ response to 30 μM AA in hCMEC/D3 cells. (B) Mean ± SE of the amplitude of ETYA- and AA-induced elevations in [Ca²⁺]_i.