Table 1.
Pat. No. | Age at PRRT Start | Sex | Tumor Type | Primary Tumor Localization | Ki-67 Index | Genotype | Indication for PRRT | Metastases | Previous Therapy | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Surgery | RT | 131I-MIBG | ChT | |||||||||
1 | 61 | F | PGL | Retroperitoneum | 5% | SDHB | Sympt | Retroper lgll, Liver, Bone | + | + | - | - |
2 | 33 | F | PGL | Urinary bladder | 10% | SDHD | NA | Mediast lgll, Neck, Heart | + | - | - | - |
3 | 24 | M | PGL | Retroperitoneum | <2% | Sporadic | Sympt | Retroper lgll, Bone | + | + | + | - |
4 | 67 | M | PGL | Aortic bifurcation | 15% | SDHB | PD | Bone | - | + | + | - |
5 | 53 | F | PCC | 2% | Sporadic | Sympt | Liver | + | - | - | - | |
6 | 25 | M | PGL | Retroperitoneum | NA, 4/10HPF | NA | PD | Bone | + | + | - | + |
7 | 56 | M | PCC | 12% | NA | PD | Retroper lgll, Bone | + | + | - | - | |
8 | 71 | F | PGL | Liver | 25% | Sporadic | NA | Bone | + | - | - | - |
9 | 70 | F | PGL | Kidney | 20% | NA | PD | Bone | + | + | + | - |
10 | 25 | M | PGL | Retroperitoneum | 25% | SDHB | NA | Liver, Bone, Lung | - | - | - | - |
11 | 56 | F | PCC | 30% | NF1 | PD | Liver, Bone | + | - | - | - | |
12 | 59 | F | PGL | Retroperitoneum | NA | NA | PD | Bone, Mediastinal lgll | + | + | + | - |
13 | 55 | M | PCC | 22% | NA | Sympt | Bone | - | + | - | - | |
14 | 65 | F | PGL | Cauda equina | 13% | Sporadic | PD | 0 | + | + | - | - |
15 | 62 | M | PCC | <1% | NA | Sympt | Liver, Bone, Lung | + | + | - | - | |
16 | 67 | M | PGL | Aortic bifurcation | 5% | NA | PD | Liver, Bone | + | - | - | - |
17 | 80 | M | PCC | <1% | SDHA | Sympt | Retroper lgll. Liver, Lung, Bone | + | - | + | - | |
18 | 39 | F | PCC | 3% | SDHB | NA | Retroper and mediastinal lgll, Lung | - | + | - | - | |
19 | 72 | M | PCC | 1% | NA | NA | Liver, Bone | + | - | - | - | |
20 | 63 | M | HNPGL | Bilateral neck | NA | SDHD | Sympt | 0 | - | + | - | - |
21 | 79 | M | PCC | NA | NF1 | PD | Bone | + | + | + | - | |
22 | 31 | M | HNPGL | Bilateral neck | NA | NA | Sympt | Liver, Bone | - | + | - | - |
F, female; M, male; PCC, pheochromocytoma; PGL, paraganglioma; HNPGL, head and neck paraganglioma; NA, not available; Sympt, symptomatic; Retroper lgll, Retroperitoneal lymph node metastases; Mediast lgll, Mediastinal lymph node metastases: RT, Radiotherapy; ChT, Chemotherapy.