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. 2019 Jul 18;20(14):3514. doi: 10.3390/ijms20143514

Figure 1.

Figure 1

Potential signaling pathway between expression of bone morphogenetic protein receptor type II, HDL cholesterol, and vascular remodeling in pulmonary arterial hypertension. Arrows represent stimulation, T-bars represent inhibitory effect. ABCA1—ATP-binding cassette transporter 1, BMPR2—bone morphogenetic protein receptor type II, IL—interleukin, miRNA—microRNA, PAH—pulmonary arterial hypertension, PASMCs—pulmonary artery smooth muscle cells, PPAR-γ—peroxisome proliferator-activated receptor gamma, TNFα—tumor necrosis factor alpha.