Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 14;20(14):3457. doi: 10.3390/ijms20143457

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

rHSPE1, BeWo GFP-iEV, and BeWo HSPE1 KO-iEV induced T_reg differentiation from CD4⁺ Th cells. (A) Representative FACS dot plot showing the expanded T_reg cell population (defined as CD25⁺CD127^lo) upon rHSPE1 treatment (x-axis showing the expression of CD25, y-axis showing the expression of CD127). (B) Concentration dependent T_reg cell expansion upon rHSPE1 treatment. (C) T_reg cell expansion upon GFP control transfected-derived iEVs (abbreviated as GFP) and HSPE1 KO-derived iEVs (abbreviated as HSPE1-KO).