BC |
Breast cancer |
mBC |
Metastatic breast cancer |
TNBC |
Triple-negative breast cancer |
CBDCA |
Carboplatin |
CDDP |
Cisplatin |
SLC31A1 |
High Affinity Copper Uptake Protein 1 |
ATP7B |
Copper-Transporting P-type Adenosine Triphosphate |
ICL |
Inter-DNA cross-link |
SSB |
Single-strand break |
DSB |
Double-strand break |
HR |
Homologous recombination repair |
BER |
Base excision repair |
HRD |
Homologous recombination deficiency |
NHEJ |
Non-homologous end joining |
BRCA1 |
Breast Cancer Type 1 Susceptibility Protein |
BRCA2 |
Breast Cancer Type 2 Susceptibility Protein |
ORR |
Objective response rate |
OS |
Overall survival |
PFS |
Progression-free survival |
PARP |
Poly(ADP-ribose) polymerase |
pCR |
Pathologic complete response |
EFS |
Event-free survival |
DFS |
Disease-free survival |
RCB |
Residual cancer burden |
NPM1 |
Nucleophosmin |
OGG1 |
8-Oxoguanine DNA glycosylase |
UNG |
Uracil-DNA-glyucosylase |
Polβ |
Polymerase β |
ROS |
Reactive oxygen species |
8oxoG |
Oxidized guanine |
EFI |
Event-free survival |