Table 3.

Specific gene mutations and the efficacy of ICI treatment.

Cancer	Gene Mutations	Efficacy of ICI Treatment?	Reference
NSCLC	EGFR	No	[42,43]
	ALK	No	[42]
	STK11	No	[22]
	TP53	Yes	[44]
	KRAS	Yes	[45]
Melanoma	PTEN	Yes	[46]
	SERPINB3, SERPINB4	Yes	[47]
RCC	PBRM1	Yes	[48]

ICI, immune checkpoint inhibitor; NSCLC, non-small cell lung cancer; RCC, renal cell cancer.