Table 3.
Genotypes of H. pylori strains and clinical outcome.
| Genotype | GAST 1 (%) | PUD 2 (%) | GERD 3 (%) | p-Value |
|---|---|---|---|---|
| n = 27 | n = 6 | n = 31 | ||
| Vac1 genotypes 4 | ||||
| s1m1 | 7 (25.9) | 3 (50) | 4 (12.9) | 0.11 |
| s1m1/s1m2 | 2 (7.4) | 0 | 1 (3.2) | 0.64 |
| s1m2 | 9 (33.3) | 3 (50) | 11 (35.5) | 0.74 |
| s2m2 | 7 (25.9) | 0 | 11 (35.5) | 0.2 |
| s2m1/s2m2 | 2 (7.4) | 0 | 1 (3.2) | 0.64 |
| s2m1 | 0 | 0 | 1 (3.2) | - |
| negative | 1 (3.7) | 0 | 0 | - |
| cagA status | ||||
| positive | 16 (59.3) | 5 (83.3) | 16 (51.6) | 0.35 |
| negative | 11 (40.7) | 1 (16.7) | 15 (48.4) | |
| iceA alleles | ||||
| iceA1 | 6 (22.2) | 3 (50) | 14 (45.2) | 0.14 |
| iceA2 | 10 (37.0) | 3 (50) | 8 (35.8) | 0.42 |
| iceA1+2 | 1 (3.7) | 0 | 2 (6.5) | 0.75 |
| negative | 10 (37.0) | 0 | 7 (22.6) | 0.14 |
| vacA s1m1/cagA+ | 7 (25.9) | 3 (50.0) | 4 (12.9) | 0.11 |
| vacAs1m2/cagA+ | 6 (22.2) | 2 (33.3) | 9 (29.0) | 0.78 |
| vacAs2m2/cagA+ | 1 (3.7) | 0 | 2 (6.5) | 0.75 |
| vacAs1m1/cagA− | 1 (3.7) | 0 | 1 (3.2) | 0.89 |
| vacAs1m2/cagA− | 4 (14.8) | 1 (16.7) | 2 (6.5) | 0.53 |
| vacAs2m2/cagA− | 6 (22.2) | 0 | 10 (32.3) | 0.23 |
1 GAST—gastritis/duodenitis; 2 PUD—peptic ulcer disease (gastric/duodenal); 3 GERD—gastroesophageal reflux disease; 4 untyped m-region was found in three samples (s1m0).