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Principal clinical biomarkers detectable by extracellular vesicles (EVs).
| Biomarkers | N Patients | Methodology | Sensitivity (%) | Specificity (%) | Reference |
|---|---|---|---|---|---|
| EGFR T790M | 23 | PNAClamp™ | 100 | 100 | Hur et al. [63] |
| PD-L1 expression | 8 | ddPCR™ | - | - | Del Re et al. [132] |
Abbreviations: PNAClamp™, peptide nucleic acid (PNA)-mediated PCR-EGFR Mutation Detection Kit; ddPCR™, Droplet Digital ™ PCR.
