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. 2019 Jul 23;20(14):3605. doi: 10.3390/ijms20143605

Figure 1.

Figure 1

Protective function of resveratrol on follicle number and development in the cyclophosphamide-induced premature ovarian failure (POF) model. (A): The mouse weight, ovarian weight, and ovary/mouse relative weight ratio in control, POF, resveratrol (RES) 20mg/kg, and RES 40mg/kg groups after 28 days of continuous lavage, individually; (B): the total weights of mice per week in different treated groups; (C): the follicles were observed after HE staining, the scale bar is 200μm; (D): all levels of follicle number were counted by tissue slice; (E,F): the rate of follicle atresia and the primordial follicular rate vs. the total number of follicles in each group; (G–I): the mRNA and protein expression levels of Mvh and Oct4 in each group. ** p < 0.01, and *** p < 0.001. vs the control group, # p < 0.05, ## p< 0.01 and ### p < 0.001 vs. the POF group.