Figure 2.
Resveratrol treatment relieves oxidative stress and benefits germline cells in POF ovaries. (A): The mRNA levels of superoxide dismutase 2 (SOD2), glutathione peroxidase (GPx), and catalase (CAT) in vivo; (B–D): the enzyme activity changes in total SOD, SOD2, GPx, and CAT in vivo; (E,F): the concentration alteration of malondialdehyde (MDA) and reactive oxygen species (ROS); (G): the mRNA levels of SOD2, GPx, and CAT; (H–J): the mRNA and protein levels of Mvh and Oct4 cultured with RES in vitro. ** p < 0.01, and *** p < 0.001 vs. the control group, # p < 0.05, ## p < 0.01 and ### p < 0.001 vs. the POF group.