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Proposed role for cardiolipin in ATP synthasome formation and mPTP opening. ANT, adenine nucleotide translocator; CL, cardiolipin; CLox, oxidized cardiolipin; Cyp D, cyclophilin D; IMM, inner mitochondrial membrane; mPTP, mitochondrial permeability transition pore; PiC, phosphate carrier. For details, see the text.
