Table 2.
bulk-RNAseq of Whole Individuals | bulk-RNAseq with Prior Selection | scRNAseq | |
---|---|---|---|
What can I do? | |||
Gain cell type specific gene expression | − | +/− | + |
Identify overall gene expression profile | + | − | − |
What do I need? | |||
Prior knowledge about the tissue or cells of interest | − | + | − |
Transgenic organisms/fluorescently labeled cells | − | + | − |
Specific technique to obtain tissue/cells | − | +/− | + |